Meloxicam (By mouth)

Comfort Pac with Meloxicam, Mobic, Vivlodex

Capsule, Liquid, Tablet

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
• You may take this medicine with or without food. If this medicine upsets your stomach, take it with food or milk.
• Capsule or tablet: Swallow whole. Do not crush, break, or chew it.
• Oral liquid: Shake the bottle gently before use. Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
• Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Do not use aspirin or any other NSAID medicine (including diflunisal, salsalate) unless your doctor says it is okay.
• Do not take the oral liquid together with sodium polystyrene sulfonate. Meloxicam oral liquid contains sorbitol, which may cause a serious bowel problem if taken with sodium polystyrene sulfonate.
• Some medicines can affect how meloxicam works. Tell your doctor if you are using any of the following:
  • Cholestyramine, cyclosporine, digoxin, lithium, methotrexate, pemetrexed
  • Blood pressure medicine
  • Blood thinner (including warfarin)
  • Diuretic (water pill)
  • Medicine to treat depression
  • Steroid medicine (including hydrocortisone, methylprednisolone, prednisolone, prednisone)

• Tell your doctor if you are pregnant or breastfeeding. Do not use this medicine during the later part of a pregnancy unless your doctor tells you to.
• Tell your doctor if you have kidney disease, liver disease, asthma, blood circulation problems, heart disease, high blood pressure, heart failure, or a history of ulcers or other stomach problems. Tell your doctor if you smoke or drink alcohol regularly.
• This medicine may cause the following problems:
  • High risk of blood clots, heart attack, stroke, or heart failure
  • High risk of stomach or bowel bleeding
  • High blood pressure
  • Liver or kidney problems
  • High potassium levels in the blood
  • Serious skin reactions
• Tell your doctor if you are trying to get pregnant. Some women who take this medicine have trouble getting pregnant.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Blistering, peeling, red skin rash
• Change in how much or how often you urinate, painful urination
• Chest pain, trouble breathing, coughing up blood
• Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
• Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
• Rapid weight gain, swelling in your hands, ankles, or feet
• Severe stomach pain, vomiting blood or material that looks like coffee grounds, bloody or black, tarry stools
• Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

• Mild nausea, diarrhea, heartburn

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088