Ocrelizumab (By injection)
Treats multiple sclerosis.
OcrevusThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to ocrelizumab.
How to Use This Medicine:
- Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
- A nurse or other health provider will give you this medicine.
- This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
- This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor for instructions.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Some medicines can affect how ocrelizumab works. Tell your doctor if you are using any of the following:
- Daclizumab, fingolimod, mitoxantrone, natalizumab, or teriflunomide
- Steroid medicine
- This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines.
Warnings While Using This Medicine:
- It is important to tell your doctor if you are pregnant or planning to become pregnant before using this medicine. Use an effective birth control during treatment and for 6 months after your treatment ends.
- Tell your doctor if you are breastfeeding or if you have liver disease (including hepatitis B), cancer, or any type of infection.
- This medicine may cause the following problems:
- Infusion reactions, which can be life-threatening
- Increase risk for infection, including progressive multifocal leukoencephalopathy
- Increase risk for cancer (including breast cancer)
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Fast, pounding, or uneven heartbeat
- Fever, chills, cough, runny or stuffy nose, sore throat, body aches
- Lightheadedness, dizziness, fainting
- Trouble breathing, headache, nausea
- Warmth or redness in your face, neck, arms, or upper chest
If you notice these less serious side effects, talk with your doctor:
- Back pain
- Feeling depressed or sad
- Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 7/4/2018
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