COMPLETE TAVR
Randomized, Comparative Effectiveness Study of Staged Complete Revascularization with Percutaneous Coronary Intervention to Treat Coronary Artery Disease vs Medical Management Alone in Patients with Symptomatic Aortic Valve Stenosis undergoing Elective Transfemoral Transcatheter Aortic Valve Replacement
Condition: Transcatheter Aortic Valve Replacement (TAVR) - Aortic Stenosis
Principal Investigator: Wayangankar, Siddharth
NCT04634240
CATALYST
Prospective, randomized, multicenter active control worldwide trial. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device and a commercially available NOAC medication
Condition: Amulet device - Atrial Fibrillation
Principal Investigator: Rama, Pamela
NCT04226547
APOLLO
Transcatheter Mitral Valve Replacement with the Medtronic Intrepid™ TMVR System in patients with severe symptomatic mitral regurgitation
Condition: Transcatheter Mitral Valve Replacement (TMVR) - Mitral Valve Regurgitation
Principal Investigator: Satpathy, Ruby / Bates, Nathan
NCT03242642
REPAIR MR
Percutaneous MitraClipTM Device or Surgical Mitral Valve Repair in Patients with Primary Mitral Regurgitation who are Candidates for Surgery
Condition: MitraClipTM Device - Severe Primary Mitral Regurgitation
Principal Investigator: Satpathy, Ruby
NCT04198870
PROGRESS CAP
The PROGRESS Trial - Continued Access
Condition: Transcatheter Aortic Valve Replacement (TAVR) - Aortic Stenosis
Principal Investigator: Satpathy, Ruby
ENGULF
A Safety and Feasibility Single-Arm Study of a Novel Catheter Thrombectomy Device For the Treatment of Pulmonary Embolism
Condition: Hēlo PE Thrombectomy System- Pulmonary Embolism (PE)
Principal Investigator: Wayangankar, Siddharth
NCT05597891
SIMPLAAFY
WM FLX™ Pro with Alternative Post-Implant Monotherapy Acceptance
Condition: WATCHMAN FLX Pro Device - Atrial Fibrillation (AFib)
Principal Investigator: Satpathy, Ruby
NCT06521463
VERITAS
Pre-market IDE study of the Amulet™ 2 LAA Occluder
Condition: Amulet 2 device - Atrial Fibrillation
Principal Investigator: Satpathy, Ruby
NCT06707688
LeAAPS
Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial
Condition: AtriClip® LAA Exclusion System - Atrial Fibrillation (AF)
Principal Investigator: Pirris, John
NCT05478304
ENVISION
Evaluation of the Navitor Transcatheter Heart Valve in Low and Intermediate Risk Patients who have Severe, Symptomatic, Aortic Stenosis Requiring Aortic Valve Replacement
Condition: NavitorTM Transcatheter Aortic Valve Implantation (TAVI) System - Aortic Stenosis
Principal Investigator: Wayangankar, Siddharth
NCT05932615
REDUCE PAS
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients with Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
Condition: GORE® CARDIOFORM Septal Occluder - Patent Foramen Ovale (PFO) and Cryptogenic Stroke
Principal Investigator: Wayangankar, Siddharth
NCT03821129
DEXTERITY
Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation after Thrombus Removal to Yield Benefit in Acute Femoropopliteal
Condition: Deep Vein Thrombosis (DVT)
Principal Investigator: Gummadi, Bharat
NCT04862468
MICRA AV PAS
Micra AV Transcatheter Pacing System Post-Approval Registry
Condition: Medtronic product registry
Principal Investigator: McKillop, Matthew
NCT04253184
ADVENT PAS
Prospective, Multi-Site Safety and Effectiveness Post-Approval Study of FARAPULSE Pulse Field Ablation in Paroxysmal Atrial Fibrillation
Condition: FARAPULSE™ Pulsed Field Ablation System - Paroxysmal Atrial Fibrillation (PAF)
Principal Investigator: McKillop, Matthew
NCT06431815
OMNY AF
Assessment of Safety and Effectiveness in Treatment Management of Paroxysmal Atrial Fibrillation with the BWI Pulsed Field Ablation System with OMNYPULSE™ Catheter
Condition: BWI OMNYPULSE™ PFA Platform - Paroxysmal Atrial Fibrillation (PAF)
Principal Investigator: Ruisi, Christopher
NCT06455098
SOS-AMI
Multi-center, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of self-administered subcutaneous selatogrel for prevention of all-cause death and treatment of acute myocardial infarction in subjects with a recent history of acute myocardial infarction
Condition: Acute Myocardial Infarction
Principal Investigator: Davuluri, Ashwini
NCT04957719
ARTEMIS
Effects of ziltivekimab versus placebo on cardiovascular outcomes inpatients with acute myocardial infarction
Condition: Acute Myocardial Infarction
Principal Investigator: Agarwal, Nayan
NCT06118281
HERMES
Phase 3 Cardiovascular Outcome Trial. (CVOT) using Ziltivikamab in patient with HFmrEF and HFpEF and an elevated hs-CRP (Greater than or equal to 2 mg/L)
Condition: Heart Failure and Systemic Inflammation
Principal Investigator: Davuluri, Ashwini
NCT05636176
CREST-2 Registry
The registry will collect information on key co-morbidities and limit the outcome measures to essential, easily used standardized measures that are commonly part of carotid trials.
Condition: Carotid Artery Stenosis Registry
Principal Investigator: Wayangankar, Siddharth
NCT02240862
BACKBEAT
Bradycardia pacemaker with AV interval modulation for Blood pressure treatment
Condition: Atrioventricular Interval Modulation (AVIM) - High Blood Pressure (Hypertension)
Principal Investigator: Vora, Aaditya
NCT06059638