Etanercept-ykro (By injection)
Etanercept-ykro (ee-TAN-er-sept - ykro)
Treats rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, and plaque psoriasis.There may be other brand names for this medicine.
When This Medicine Should Not Be Used:
This medicine is not right for everyone. Do not use it if you had an allergic reaction to etanercept-ykro or if you have a blood infection (sepsis).
How to Use This Medicine:
- Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.
- A nurse or other health provider will give you this medicine.
- You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
- You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. Do not inject into skin areas that are red, hard, bruised, tender, thick, or scaly, in areas with scars or stretch marks, or in areas affected by psoriasis.
- Allow the medicine to come to room temperature for at least 30 minutes before you use it. Do not warm it in any other way.
- Check the liquid in the prefilled syringe. It should be colorless or slightly yellow and may contain small, white or almost clear particles. Do not use the medicine if the liquid is cloudy, discolored, or has particles in it that are not small, white or almost clear. Do not shake.
- Do not remove the needle cap from the prefilled syringe until you are ready to use it.
- Use a new needle and syringe each time you inject your medicine.
- You might not use all of the medicine in each prefilled syringe. Use each prefilled syringe only one time. Do not save an open syringe.
- This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
- Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
- If you store this medicine at home, keep it in the refrigerator. Do not freeze. You may also store this medicine at room temperature, away from heat and light for 14 days. Do not return it back to the refrigerator once kept at room temperature. Throw away any unused medicine after 14 days. Do not store the prefilled syringe in extreme heat or cold, including keeping it in your vehicle's glove box or trunk.
- Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Some medicines can affect how etanercept-ykro work. Tell your doctor if you are using any of the following:
- Abatacept, anakinra, cyclophosphamide, sulfasalazine
- Steroid medicine (including dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone)
- This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines.
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant or breastfeeding, or if you have diabetes, heart failure, liver problems (including hepatitis), multiple sclerosis or any nervous system problem, Wegener's granulomatosis, or a history of cancer, seizures, or Guillain-Barré syndrome. Tell your doctor if you have been recently exposed to chickenpox.
- This medicine may cause you to get infections more easily. Tell your doctor if you have any type of infection (including tuberculosis, hepatitis B) before you start treatment. Also tell your doctor if you or a family member has a history of tuberculosis (TB). Take precautions to avoid illness. Wash your hands often.
- This medicine may cause the following problems:
- Nervous system problems
- Increased risk of cancer, including lymphoma, leukemia, and skin cancer
- Heart failure
- Autoimmune problems, including lupus-like syndrome and autoimmune hepatitis
- You will need a skin test for TB before you start using this medicine. Tell your doctor if you or anyone in your home has ever had a positive reaction to a TB skin test.
- This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Change in how much or how often you urinate, painful or difficult urination
- Change in vision, eye pain
- Chest pain, coughing up blood, muscle pain, night sweats, weight loss
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Fever, chills, cough, runny or stuffy nose, sore throat, body aches
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet
- Skin changes or growths, red, scaly patches on the skin
- Sores or white patches on your lips, mouth, or throat
- Swollen glands in your neck, armpits, or groin
- Trouble breathing, cold sweat, blue skin, swelling in your hands, ankles, or feet
- Unusual bleeding, bruising, tiredness, or weakness
If you notice these less serious side effects, talk with your doctor:
- Pain, redness, swelling, itching, bleeding, or bruising where the shot was given
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 10/10/2019
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